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Atopic Dermatitis Epidemiology and Pathogenesis Update
特应性皮炎的流行病学和发病机理
AtopicDermatitis:
EpidemiologyandPathogenesisUpdate
LawrenceF.Eichen eld,MD,*CharlesN.Ellis,MD,
AnthonyJ.Mancini,MD, AmyS.Paller,MD,§andEricL.Simpson,MD,MCR
Theprevalenceofatopicdermatitis(AD)hasincreasedmarkedlyintheUnitedStatesoverthepast5decades,withcurrentreportsvaryingfrom10%to20%prevalenceinUSchildren,andnewdiagnosesareestimatedatalmost11%peryear.RecentresearchinADpathophysiologyandpathogenesishasdemonstratedthatADisassociatedwithepidermalbarrierdysfunctionandthatmutationsinthe laggringeneareimplicat
Atopic Dermatitis Epidemiology and Pathogenesis Update
特应性皮炎的流行病学和发病机理
AtopicDermatitis:
EpidemiologyandPathogenesisUpdate
LawrenceF.Eichen eld,MD,*CharlesN.Ellis,MD,
AnthonyJ.Mancini,MD, AmyS.Paller,MD,§andEricL.Simpson,MD,MCR
Theprevalenceofatopicdermatitis(AD)hasincreasedmarkedlyintheUnitedStatesoverthepast5decades,withcurrentreportsvaryingfrom10%to20%prevalenceinUSchildren,andnewdiagnosesareestimatedatalmost11%peryear.RecentresearchinADpathophysiologyandpathogenesishasdemonstratedthatADisassociatedwithepidermalbarrierdysfunctionandthatmutationsinthe laggringeneareimplicat