immune

学习目标 掌握 HSC功能特征 掌握阳性和阴性选择的生物学意义 罗列 T 、 B 细胞的主要表面标志，并掌握其功能:-TCR-CD3 complex; -BCR complex; -coreceptors; -co-stimulatory molecules and co-stimulatory receptors

掌握T、B细胞的分类方法与功能 掌握 NK 细胞的特点

I 免疫系统:

概述

Tissues and organs Cells Molecules

免疫细胞的类型Cells of adaptive immune systemAntigen specific lymphocytes (T,B cells) Antigen presenting cells抗原提呈细胞

Cells of innate immune systemMononuclear phagocytes 单核-巨噬细胞 Granulocytic cells 粒细胞 Mast cells 肥大细胞 Natural killer cells 自然杀伤细胞 Platelets 血小板4

Hematopoietic Stem Cell (HSC ) 造血干细胞 H

学习目标 掌握 HSC功能特征 掌握阳性和阴性选择的生物学意义 罗列 T 、 B 细胞的主要表面标志，并掌握其功能:-TCR-CD3 complex; -BCR complex; -coreceptors; -co-stimulatory molecules and co-stimulatory receptors

掌握T、B细胞的分类方法与功能 掌握 NK 细胞的特点

I 免疫系统:

概述

Tissues and organs Cells Molecules

免疫细胞的类型Cells of adaptive immune systemAntigen specific lymphocytes (T,B cells) Antigen presenting cells抗原提呈细胞

Cells of innate immune systemMononuclear phagocytes 单核-巨噬细胞 Granulocytic cells 粒细胞 Mast cells 肥大细胞 Natural killer cells 自然杀伤细胞 Platelets 血小板4

Hematopoietic Stem Cell (HSC ) 造血干细胞 H

Flow-Cytometric Immune Function 41

5

Flow-Cytometric Immune Function Methodologyfor Human Peripheral Blood Dendritic Cells

Kerstin Willmann

1. Introduction

The following describes the use of ow cytometry to detect the immune response of circulating CD11c+ and CD11c– (CD123 high, pre-DC2) dendritic cells on a single-cell level (1–4). Flow cytometry is an analytical and prepara-tive tool for immunology (5,6). Its use has rapidly advanced the accurate quanti- cation of periphera

Mitochondrial DNA stress primes the antiviral innate immune response

A.Phillip West1,William Khoury-Hanold2,Matthew Staron2,Michal C.Tal2{,Cristiana M.Pineda1,Sabine b87cb1ade2bd960591c67714ng1,

Megan Bestwick1{,Brett A.Duguay3,Nuno Raimundo1{,Donna A.MacDuff4,Susan M.Kaech2,5,James R.Smiley3,

Robert E.Means1,Akiko Iwasaki2,5&Gerald S.Shadel1,6

Mitochondrial DNA(mtDNA)is normally present at thousands of copies per cell and is packaged into several hundred higher-order structures termed nucleoids1.The abundant mtDNA-binding pro-

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Report Information from ProQuest

October 21 2014 22:31

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www.library.utoronto.ca

Table of contents

1. Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer..................................................1

Bibliography..............................................................................................................

JournalofViralHepatitis,2000,7,321±326

REVIEW

HowcanthecellularimmuneresponsecontrolhepatitisBvirusreplication?

M.K.Maini1,2andA.Bertoletti1

ofLondonMedicalSchool,London,UK

1

InstituteofHepatologyand2DepartmentofSexuallyTransmittedDiseases,UniversityCollege

SUMMARY.Inthisreviewwefocusonaspectsofthevirus-

speci®ccellularimmuneresponse,althoughweshouldpointoutthatallthecomponentsoftheinnateandadaptiveimmuneresponsearelikelytoplayaroleinsuccessfulcontrolofhepatitisBvirus(HBV)infection.Weconcentrateparticularlyontherelevanceo

ImmunologyLetters125(2009)145–150

ContentslistsavailableatScienceDirect

Immunology

Letters

journalhomepage:/locate

/

ImmuneresponsesinducedbyaBacMamvirusexpressingtheE2proteinofclassicalswinefevervirusinmice

MiaoLi,Yu-FeiWang,YuWang,HuiGao,NaLi,YuanSun,Bing-BingLiang,Hua-JiQiu

DivisionofSwineInfectiousDiseases,NationalKeyLaboratoryofVeterinaryBiotechnology,HarbinVeterinaryResearchInstitute,ChineseAcademyofAgriculturalSciences,427MaduanStreet,150001Harbin,Heilongjiang,China

articleinfoabstract

Non-replicatingbaculovirus-mediatedgenet