2014 苏州海内外华人神经科学大会

Time Schedule

Garden Hotel Suzhou (南园宾馆) June 24 Tuesday 13:00-22:00 Registration 08:00-08:30 Opening Ceremony 08:30-10:10 Session 1: Drug dependence and psychiatric diseases (Chair: Lin Mei & Tao Li) 2号楼一楼 飞泉厅 5号楼一楼 10:10-10:30 Tea break 10:30-12:30 Session 2: Neural development (Chair: Guo-Li Ming & Zhi-Heng Xu) June 25 12:30-14:00 Lunch Session 3: Synaptic transmission and plasticity (Chair: Lu-Yang Wang & Guo-Qiang Bi) 荷花轩/忆江南 Wednesday 14:00-16:00 16:00-16:20 Tea break 16:20-18:00 Session 4: Stem cells (Chair: Gong Chen & Qin Shen) 2号楼一楼 飞泉厅 19:00-21:00 Welcome Banquet (Leica Party) 21:00-22:00 Business meeting 08:00-10:00 Session 5: Sensory system (Chair: Hai-Qing Zhao & Xu Zhang) 2号楼一楼 飞泉厅 2号楼二楼 思元厅 10:00-10:20 Tea break June 26 Thursday 10:20-12:20 Session 6: Neurodegenerative disease and brain disorders (Chair: Xiao-Jiang Li & Chun-Feng Liu) 12:20-14:00 Lunch 13:00-15:00 Poster Session 15:00 08:00-10:00 Free time Session 7: Pain (Chair: Zhi-Zhong Pan & Guang-Yin Xu) 荷花轩/忆江南 2号楼二楼 白云厅、清涟厅 2号楼一楼 飞泉厅 10:00-10:20 Tea break 10:20-12:20 June 27 Friday Session 8: Ion Channel Physiology and Biophysics (Chair: Michael X. Zhu & Tian-Le Xu) 12:20-14:00 Lunch 14:00-15:20 Session 9: Computational Neuroscience (Chair: Ke-Chen Zhang & David Cai) 荷花轩/忆江南 15:20-15:40 Tea break 15:40-17:40 2号楼一楼 Session 10: Neuronal injury, repair, restore, regeneration, and neuroprotection 飞泉厅 (Chair: Ri-Yi Shi & Xiao-Song Gu) 18:00-18:30 Poster award and Closing remarks 18:30-20:30 Dinner June 28 Saturday Tour/End

Scientific Program 06/25/14

08:30 – 10:10 Session 1: Drug dependence and psychiatric diseases

(Chairs: Lin Mei & Tao Li)

08:30 - 08:50

Wen-Jun Gao (Drexel University, Wen-Jun.Gao@DrexelMed.edu) Title: Mechanisms of NMDA receptor hypofunction in animal models for schizophrenia 08:50 - 09:10

Xin-Yun Lu (University of Texas Health Science Center, lux@uthscsa.edu) Title: The adipose-brain axis in major depression: susceptibility and novel therapeutics 09:10 - 09:30

Dong-Min Yin (Georgia Regents University, dyin@gru.edu)

Title: Role of Neuregulin 1 in synapse formation and transmission and its implication in schizophrenia relevant endophenotype 09:30 - 09:50

Qiang Wang (West China School of Medicine, wangqiang130@hotmail.com) Title: Decoding the genetic mechanism of brain deficits of schizophrenia in Han Chinese 09:50 - 10:10

Kun Xia (Xiangya Medical School, Central South University, xiakun@sklmg.edu.cn) Title: Genetic Study for Autism In Chinese Population

10:10 - 10:30 Tea break

10:30 – 12:30 Session 2: Neural development

(Chairs: Guo-Li Ming & Zhi-Heng Xu)

10:30 - 10:50

Hong-Jun Song (Johns Hopkins University: shongju1@jhmi.edu)

Title: Deconstructing complexity of hypothalamus ontology via clonal analysis of neural stem cells 10:50 - 11:10

Yi-Min Zou (University of California, yzou@ucsd.edu)

Title: Sonic hedgehog is a midline switch signal for commissural axon guidance 11:10 - 11:30

Juan Song (University of North Carolina, juansong@email.unc.edu) Title: A diametric mode of adult neurogenesis regulation via parvalbumin interneurons 08:00 – 08:30

Opening Ceremony and Group Picture

11:30 - 11:50

Zhi-Heng Xu (Institute of Genetics and Developmental Biology, CAS, zhxu@genetics.ac.cn)

Title: Microcephaly Associated Protein WDR62 Interacts with MEKK3 to Regulate JNK Signaling and Neural Progenitor Cell Maintenance in the Developing Neocortex 11:50 - 12:10

Xiang Yu (Shanghai Institutes for Biological Sciences, CAS, yuxiang@ion.ac.cn) Title: Oxytocin Mediates Early Experience-dependent Crossmodal Plasticity of Excitatory Synaptic Transmission in the Sensory Cortices 12:10 - 12:30

Zhen-Ge Luo (Institute of Neuroscience, CAS, zgluo@ion.ac.cn) Title: Non-apoptotic role of caspase-3 in synapse refinement

12:30 - 14:00 Lunch

14:00 - 16:00 Session 3: Synaptic transmission and plasticity

(Chairs: Lu-Yang Wang & Guo-Qiang Bi)

14:00 - 14:20

Yi Zuo (University of California, yizuo@ucsc.edu) Title: Synapse reorganization in formation of motor memory 14:20 - 14:40

Shang-Bang Gao (Lunenfeld-Tanenbaum Research Institute, gao@lunenfeld.ca) Title: Persistent Neural Activity Sustains C. elegans Locomotion via NCA Channel 14:40 - 15:00

Zheng-Ping Jia (University of Toronto, zhengping.jia@sickkids.ca) Title: Molecular mechanisms governing spine plasticity 15:00 - 15:20

Xiao-Wei Chen (Third Military Medical University, xiaowei_chen@tmmu.edu.cn) Title: A cerebellar inhibitory microcircuit for habituation of acoustic startle response 15:20 - 15:40

Wei Xiong (University of Science and Technology of China, xiongw1111@gmail.com)

Title: Cannabinoid restoration of heperekplexia by targeting presynaptic glycine receptors 15:40 - 16:00

Yu-Long Li (Peking University, yulong@gmail.com)

Title: Novel fluorescent sensors for spying neuronal communication

16:00 - 16:20 Tea break

06/26/14

16:20 - 18:00 Session 4: Stem cells

(Chairs: Gong Chen & Qin Shen)

16:20-16:40

Guo-Li Ming (Johns Hopkins, gming1@jhmi.edu)

Title: Function of risk genes for mental disorders in neural development 16:40-17:00

Gong Chen (Penn State University, gongchen@psu.edu) Title: In vivo reprogramming for brain repair 17:00-17:20

Zhen-Gang Yang (Fudan University, yangz@fudan.edu.cn)

Title: Transcription regulation of subcortical neural stem cells and cortical interneuron development 17:20-17:40

Xiao-Qun Wang (Biological physics of CAS, xiaoqun.wang@gmail.com) Title: Neural stem cell and neurogenesis in the embryonic neocortex 17:40-18:00

Guang-Hui Liu (Biological physics of CAS, ghliu@ibp.ac.cn)

Title: Using pluripotent stem cell to study and treat aging-associated diseases

19:00-21:00 Welcome banquet (Leica party) 21:00-22:00 Business meeting

08:00 - 10:00 Session 5: Sensory systems

(Chairs: Hai-Qing Zhao & Xu Zhang)

08:00 - 08:20

Ming-Hong Ma (University of Pennsylvania, minghong@mail.med.upenn.edu) Title: G Protein-coupled Odorant Receptors Are Polymodal Sensors Underlying Both Odorant and Mechanical Responses 08:20 - 08:40

Li-Quan Huang (Institute of Zoology, Chinese Academy of Sciences, lhuang@monell.org)

Title: The role of one heterotrimeric G protein subunit in two chemosensory systems 08:40 - 09:00

Hai-Qing Zhao (John Hopkins University, hzhao@jhu.edu)

Title: Novel protein Q8BH53 modulates olfactory transduction kinetics 09:00 - 09:20

Zhuan Zhou (Peking University, zzhou@pku.edu.cn)

Title: Intracellular TRPA1 Mediates Ca2+ Release in Dorsal Root Ganglion Neurons

09:20 - 09:40

Jun-Hai Han (Institute of Life Sciences, Southeast University, junhaihan@seu.edu.cn)

Title: Feedback regulation in Drosophila visual circuits 09:40 - 10:00

Xu Zhang (Institute of Neuroscience, CAS, xu.zhang@ion.ac.cn)

Title: Nociceptive afferent transmission is regulated by Na+,K+-ATPase function

10:00 - 10:20 Tea break

10:20 - 12:20 Session 6: Neurodegenerative diseases and brain disorders

(Chairs: Xiao-Jiang Li &Chun-Feng Liu)

10:20 - 10:40

Wen-Chen Xiong (Medical College of Georgia, WXIONG@georgiahealth.edu) Title: Impaired mitochondrial fusion and function by Vps35-deficiency in pathogenesis of Parkinson’s disease 10:40 - 11:00

Yong Shen (Florida University, yshen@rfdn.org)

Title: TNF receptor mediated distinct NF-kB signal pathways in neurodegenerative disorders 11:00 - 11:20

Shi-Hua Li (Emory University, sli@emory.edu)

Title: Age dependent chaperon activity contributes to protein misfolding mediated neurodegenerative disease 11:20 - 11:40

Zhi-Ying Wu (Huashan Hospital, zhiyingwu67@yahoo.com)

Title: Correlation between paroxysmal kinesigenic dyskinesia and proline-rich transmembrane protein 11:40 – 12:00

Wei-Dong Le (1st Affiliated Hospital, Dalian Medical University, wdle@sibs.ac.cn) Title: Epigenetic modifications of chronic hypoxia-mediated neurodegeneration in Alzheimer’s disease 12:00 – 12:20

Cheng-Jie Mao (The Second Affiliated Hospital of Soochow University, drchengjiemao@163.com)

Title: Prominent non-motor symptoms in Parkinson’s disease patients that have pain

12:20 - 14:00 Lunch 13:00 - 15:00 Poster session

06/27/14 08:00 - 10:00 Session 7: Pain

(Chairs: Zhi-Zhong Pan & Guang-Yin Xu)

08:00 - 08:20

Zhi-Zhong Pan (University of Texas MD Anderson Cancer Center, zzpan@mdanderson.org)

Title: Pain facilitation of opioid reward via an epigenetic mechanism. 08:20 - 08:40

Yuan-Xiang Tao (Rutgers University New Jersey Medical School, yt211@njms.rutgers.edu)

Title: An endogenous long noncoding RNA: a new player in neuropathic pain 08:40 - 09:00

Yu-Qing Cao (Washington University, caoy@morpheus.wustl.edu)

Title: The effect of migraine-associated ion channel mutations on primary afferent excitability. 09:00 - 09:20

Guang-Yin Xu (Suzhou University, guangyingxu@suda.edu.cn)

Title: Mysterious gaseous molecule hydrogen sulfide and chronic visceral pain 09:20 - 09:40

Yu-Qiu Zhang (Fudan University, yuqiuzhang@fudan.edu.cn) Title: SIP30 required for neuropathic pain-evoked aversion in rats 09:40 - 10:00

Yan Lv (Xijing Hospital, Fourth Military Medical University, yanlu001@fmmu.edu.cn)

Title: Circuit-specific LTD of the spinal glycinergic gate circuitry is required for the development of neuropathic allodynia after nerve injury

10:00 - 10:20 Tea break

10:20-12:20 Session 8: Ion Channel Physiology and biophysics

(Chairs: Michael X. Zhu & Tian-Le Xu)

10:20- 10:40

Jie Zheng (University of California Davis School of Medicine, jzheng@ucdavis.edu) Title: Heat activation of TRP channels 10:40- 11:00

Xian-Zhong Shawn Xu (University of Michigan, shawnxu@umich.edu) Title: Sensory transduction and channels in C. elegans 11:00-11:20

Michael X. Zhu (The University of Texas Health Science Center, mikexzhu@gmail.com)

Title: Dissecting the computing role of TRPC4 channels in neurons 11:20-11:40

Jing Yao (Wuhan University, jingyao@mail.hust.edu.cn)

Title: Proton enhances the activity of TRPV3 channel through modification of 2-Aminoethoxydiphenyl borate. 11:40-12:00

Xu-Hui Zeng (Nanchang University, xuhuizeng@hotmail.com）

Title: LRRC52 is a functional component to constitute potassium channel in sperm 12:00-12:20

Ye Yu (Shanghai Jiaotong University, yuye@shsmu.edu.cn） Title: Mechanistic insights into the activation of P2X4 receptor

12:30-14:00 Lunch

14:00 - 15:20 Session 9: Computational Neuroscience (Chairs: Ke-Chen Zhang & David Cai) 14:00-14:20

Ke-Chen Zhang (kzhang4@jhmi.edu, kzhang4@jhmi.edu) Title: Adaptive stimulus design and optimal population codes 14:20-14:40

Bai-Lu Si (Shenyang Institute of Automation, CAS, sibailu@sia.ac.cn) Title: Development of grid cells in medial entorhinal cortex: a model 14:40-15:00

Yu-Guo Yu (Fudan University, yuyuguo@fudan.edu.cn)

Title: Sparse coding and lateral inhibition arising from balanced and unbalanced dendrodendritic excitation and inhibition 15:00-15:20

Dong-Zhuo Zhou (Shanghai Jiaotong University, zdz@sjtu.edu.cn） Title: Sampling hazards in data inference of spatiotemporal dynamics

15:20-15:40 Tea break

15:40-17:40 Session 10: Neuronal injury, repair, restore, regeneration and

neuroprotection

(Chairs: Ri-Yi Shi & Xiao-Song Gu ) 15:40-16:00

Wu-Tian Wu (The University of Hong Kong, wtwu@hkucc.hku.hk) Title: Survival and regeneration of motor neurons after axonal injury 16:00-16:20

Jin-Hui Chen (Indiana University, chen204@iupui.edu)

06/28/14

Title: In vivo reprogramming of reactive glia into neurons in the cortex following traumatic brain injury 16:20-16:40

Ri-Yi Shi (Purdue University US, riyi@purdue.edu) Title: Role of Acrolein in Spinal Cord Injury 16:40-17:00

Xiao-Song Gu (Nantong University, nervegu@ntu.edu.cn) Tilte: Tissue-engineered nerve for peripheral nerve regeneration 17:00-17:20

Yao-Bo Liu (Suzhou University, liuyaobo@suda.edu.cn) Title: NB-3 signaling in axonal projection and plasticity 17:20-17:40

Hai-Tao Wu (Academy of military medical sciences, waters97@163.com)

Title: Signaling mechanisms of neural development and synaptic plasticity at the neuromuscular junction

18:00-18:30 Poster award and closing remarks 18:30-20:30 Dinner

Tour/End Poster Session

P-01 Zhi Yang, Xuewen Cheng, Ren-Chao Chen, Lei Tian, Jie Wang, Pengfei Li, Shaoran Wang,

Jing Zhang, Lu Wang, Ya Shen, Xiaohui Wu, Bing Fang, and Zhi-Qi Xiong

ADAM10 is required for microtubule structure and radial migration of cortical neurons by the regulation of doublecortin expression P-02 Yao Tian, Lina Liu, Wei Xie, Junhai Han

Neurexin Regulates Lamina Neurons Axonal Tiling Through Ephrin/EPH Signaling in Drosophila P-03 Sisi Wang, Fei Luo

Breaking the bottleneck: the effect of short-term meditation training on attentional blink performance

P-04 Fang Xu, Dongqing Shi, Pakming Lau, Guoqiang Bi

Emergence of spatiotemporal neuronal firings in cultured hippocampal networks

P-05 Xianghui Zhao, Jinxiang Dai, Yue Ma, Yajing Mi, Daxiang Cui, Gong Ju, Wendy B. Macklin,

Weilin Jin

Dynamics of Tet hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation P-06 Dingxi Zhou, You Yu

JIP1 in neuronal polarization

P-07 Hai Zou, Sanzhong Li, Zhengwu Peng, Beiyu Chen, Xianghui Zhao, Yazhou Wang, Fang Gao,

Zhengping Zhang

Enforced microRNA-9 expression promotes the migration of human U87 glioblastoma cells through regulating MMPs and N-cadherin P-08 Hongxue Luo, Jun wan

Analysing of microRNA profiles in cortex of APPswe/PS1ΔE9 mice and the role of miR-99b/100 in the pathogenesis of Alzheimer’s disease P-09 Xiaoyang Ye, Wan Jun

IL23/IL17-mediated Inflammation Induced by AβAccelerates Alzheimer’s disease Development P-10 Xiangnan Zhang, Yang Yuan, Lei Jiang, Zhe Shen, Yanrong Zheng,Tian Deng, Wei-Wei Hu,

Zhong Chen

Endoplasmic Reticulum Stress Induced by Tunicamycin and Thapsigargin Protects against Transient Ischemic Brain Injury: Involvement of PARK2-dependent Mitophagy P-11 Wei-Wei HU, Jing ZHANG, Jing MA, Zhong CHEN

IL-1β inhibits remyelination in subcortical ischemic vascular dementia through blocking oligodendrocyte precursor cells migration P-12 Sun Ya-Bin, Wang Jin-Yan, Luo Fei

Which induce more empathy? Differential embodied and brain reactions to painful faces versus needle-pricked arms

P-13 Hong-Hong ZHANG, Ji HU, You-Lang ZHOU, Shu-Fen HU, Xing-Hong JIANG, Guang-Yin

XU

Toll-like receptor 4 mediates gastric hypersensitivity through an epigenetic mechanism in diabetic rats

P-14 Chun Zheng, Jin-Yan Wang, Fei Luo

The pain-related information could induce attentional blink in single and dual-task of rapid serial visual presentation

P-15 You-Lang Zhou, Guo-Qing Jiang, Jinrong Wei, Honghong Zhang, Xiaowen Meng, Wei Chen,

Hongyan Zhu, Shufen Hu, Xinghong Jiang and Guang-Yin Xu

Suppression of p65 attenuates bone cancer pain through downregulation of P2X3 receptors in rats

P-16 Kefu Liu, Nuomin Li, Yuanyuan Ran, Zhenzhen Sun, Hong Qing

Glycation of tau protein promotes the formation of filaments during tau phosphorylation P-17 Xue Dong, Stephen A. Engel, Min Bao

The time course of contrast adaptation measured with a new method: Detection of ramped contrast

P-18 Ya-Hui Man, Yan Liu, Qian Chen, Wen-Jian Wu

The Study on Olfactory-Based Biomimetic Nanosensors P-19 Xiaowei Li, Pak-Ming Lau and Guo-Qiang Bi

Dopaminergic modulation of reverberatory activity in cultured neuronal networks P-20 Cheng Xu, Huijing Liu, Wei Wu, Pak-Ming Lau and Guo-Qiang Bi

Hydrogen sulfide-mediated chronic abdominal pain in rats with diabetic gastroparesis

Super-resolution fluorescence imaging of synaptic glutamate receptors and their reorganization in homeostatic plasticity

P-21 Zhu Si, Yuntao Liu, Pak-Ming Lau & Guo-Qiang Bi

Transport of Pseudorabies virus (PRV) in cultured hippocampal neurons P-22 谢勤

一种可用于脑神经网络分析的有向网络分解算法

P-23 Pu-Ming Zhang, Yong-Hua Li, Xin-Wei Gong, Hui Ren, Pei-Ji Liang

Researches on the characteristics of epileptiform discharges P-24 Jing Bi, Yicheng Xie, Shui Qing Ye, Shinghua Ding

Neuroprotective role of NAMPT in in vivo and in vitro ischemic models P-25 Hai-Feng Lu, Yi Luo, Jun Zhou, Peng-Fei Wu, Fang Wang, Jian-Guo Chen

The Surface Stability of AMPA Receptor Controls Behavioral and Synaptic Adaptations to Cocaine and Fear Conditioning

P-26 Xin-She Liu, Ying Hou, Ting-Lin Yan, Yan-Yan Guo, Wei Han, Fang-Lin Guan, Teng Chen, Tao

Li

Dopamine D3 receptors are involved in morphine-induced locomotor activity by regulating NR2B receptors in the nucleus accumbens

P-27 Haishui Shi, Xi Yin, Honghai Wu, Yuqin Hu, Li Song, Gai Xue, Yanning Hou

Long non-coding RNAs: New Participants of memory formation

P-28 Chuang Wang,Yang Lu, Peipei Lin, Tonghe Pan, Zhancheng Xue, Qinwen Wang, Wenhua Zhou,

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